Exhibit 24

POWER OF ATTORNEY

KNOW ALL BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Devinder Kumar and Harry A. Wolin, and each of them, his true and lawful attorneys-in-fact and agents, with full power of substitution and re-substitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign Advanced Micro Devices, Inc.’s Annual Report on Form 10-K for the fiscal year ended December 25, 2021, and any and all amendments thereto, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or any of them, or their or his or her substitute or substitutes, may lawfully do or cause to be done by virtue hereof.

Signature

Title

Date

/s/Lisa T. Su

President and Chief Executive Officer, Director

February 3, 2022

Lisa T. Su

/s/Devinder Kumar

Executive Vice President, Chief Financial Officer and Treasurer

February 3, 2022

Devinder Kumar

/s/Darla Smith

Corporate Vice President, Chief Accounting Officer

February 3, 2022

Darla Smith

/s/John E. Caldwell

Director, Chairman of the Board

February 2, 2022

John E. Caldwell

/s/Nora M. Denzel

Director

January 31, 2022

Nora M. Denzel

/s/Mark Durcan

Director

February 1, 2022

Mark Durcan

/s/Mike P. Gregoire

Director

February 2, 2022

Mike P. Gregoire

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/s/Joe Householder

Director

January 31, 2022

Joe Householder

/s/John W. Marren

Director

January 31, 2022

John W. Marren

/s/Abhi Y. Talwalkar

Director

January 31, 2022

Abhi Y. Talwalkar